Endotoxin for Alcohol Research: A Call for Experimental Medicine Using Lipopolysaccharide Challenge.


Journal article


E. Burnette, E. Grodin, N. Eisenberger, L. Ray
Alcohol and alcoholism, 2021

Semantic Scholar DOI PubMed
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APA   Click to copy
Burnette, E., Grodin, E., Eisenberger, N., & Ray, L. (2021). Endotoxin for Alcohol Research: A Call for Experimental Medicine Using Lipopolysaccharide Challenge. Alcohol and Alcoholism.


Chicago/Turabian   Click to copy
Burnette, E., E. Grodin, N. Eisenberger, and L. Ray. “Endotoxin for Alcohol Research: A Call for Experimental Medicine Using Lipopolysaccharide Challenge.” Alcohol and alcoholism (2021).


MLA   Click to copy
Burnette, E., et al. “Endotoxin for Alcohol Research: A Call for Experimental Medicine Using Lipopolysaccharide Challenge.” Alcohol and Alcoholism, 2021.


BibTeX   Click to copy

@article{e2021a,
  title = {Endotoxin for Alcohol Research: A Call for Experimental Medicine Using Lipopolysaccharide Challenge.},
  year = {2021},
  journal = {Alcohol and alcoholism},
  author = {Burnette, E. and Grodin, E. and Eisenberger, N. and Ray, L.}
}

Abstract

Studies of inflammation in alcohol use disorder (AUD) are overwhelmingly preclinical, and translation to clinical samples is necessary. Endotoxin administration has been used successfully in humans to study mood disorders, offering a translational, reliable and safe model that may be validated in AUD research. We argue for the use of endotoxin challenge to elucidate the interplay between AUD and inflammation.


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